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Published: 16-10-2021

Nutritional approach in the prevention and treatment of knee osteoarthritis: a systematic review

HOBRA - Brasilia Hospital, Brasília, Distrito Federal, Brazil
HOBRA - Brasilia Hospital, Brasília, Distrito Federal, Brazil
HOBRA - Brasilia Hospital, Brasília, Distrito Federal, Brazil
HOBRA - Brasilia Hospital, Brasília, Distrito Federal, Brazil
ABRAN - Associação Brasileira de Nutrologia / Brazilian Association of Nutrology, Catanduva/SP, Brazil
Osteoarthritis Knee Nutritional approach Prevention Treatment


Osteoarthritis (OA) is the most prevalent joint disease, considered the rheumatic condition with the greatest consequences in terms of socioeconomic impacts, especially knee osteoarthritis since it makes walking difficult. To date, there is no cure for OA, so available treatments aim to reduce symptoms such as pain and inflammation, maintain joint mobility, and limit the loss of function. As OA has a known inflammatory component, it is believed that nutrition can play a vital role in the prevention and ongoing management of OA. This article aims to analyze the available evidence in the prevention and treatment of knee OA with a dietary intervention that may play a potential role in the management of the disease. To carry out this literature review, articles were searched in the Scielo, Pubmed, and Bireme databases with the time frame of the last 10 years. The results showed that some nutrients, vitamins, and antioxidants are widely discussed in the literature in the treatment and prevention of the disease. Management of free radicals is necessary and the influence of nutrients and diet on cartilage and OA metabolism may represent a long-term adjuvant alternative in the treatment of patients with knee OA. Effects of dietary modifications on lipid and cholesterol profiles, adequate vitamin levels, and weight reduction in obese patients may influence the course of the disease.


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How to Cite

Santos, J. B., Mangili, L. R., Mangili, M. R., Mangili, I. R., & Ribas Filho, D. (2021). Nutritional approach in the prevention and treatment of knee osteoarthritis: a systematic review. International Journal of Nutrology, 14(4).