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Review
Published: 2022-11-14

Relationship between nutrology and oral health: a systematic review of major clinical findings

UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil
UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil
UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil
UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil / UNIPOS - Post graduate and continuing education, Dentistry department, São José do Rio Preto, São Paulo, Brazil
Nutrology Nutrition Dietetic therapy Oral health Dental care

Abstract

Introduction: Food and nutrition are fundamental in maintaining the general and oral health of populations. Health status can be affected by nutrient deficiency and vice versa. Dietary guidelines were developed to provide evidence-based food and beverage recommendations to populations to promote a diet that meets nutritional needs and prevents diet-related illness. Objective: Aimed to carry out a concise systematic review to elucidate through clinical studies the real relationship between nutrition and oral health. Methods: The rules of the Systematic Review-PRISMA Platform. The research was carried out from August to October 2022 and developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar, using scientific articles from 2005 to 2022. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 125 articles were found. In total, 75 articles were fully evaluated and 35 were included and evaluated in this systematic review. It was concluded that food and nutrition are fundamental in maintaining the general and oral health of populations. Health status can be affected by nutrient deficiency and vice versa. Nutrology can promote a diet that meets nutritional needs and prevent diet-related diseases such as tooth decay. It was evidenced that malnutrition can significantly affect oral health and vice versa. A diet lacking in nutrients can lead to the progression of oral cavity disease by altering tissue homeostasis, reducing resistance to microbial biofilm, and decreasing tissue healing. It can also affect the development of the oral cavity.

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References

  1. Isola G. The Impact of Diet, Nutrition and Nutraceuticals on Oral and Periodontal Health. Nutrients. 2020 Sep 6;12(9):2724. doi: 10.3390/nu12092724.
  2. Watanabe Y, Okada K, Kondo M, Matsushita T, Nakazawa S, Yamazaki Y. Oral health for achieving longevity. Geriatr Gerontol Int. 2020 Jun;20(6):526-538. doi: 10.1111/ggi.13921.
  3. Zohoori FV. Chapter 1: Nutrition and Diet. Monogr Oral Sci. 2020;28:1-13. doi: 10.1159/000455365.
  4. Rahman N, Walls A. Chapter 12: Nutrient Deficiencies and Oral Health. Monogr Oral Sci. 2020;28:114-124. doi: 10.1159/000455379.
  5. Achalu P, Zahid N, Sherry DN, Chang A, Sokal-Gutierrez K. A Qualitative Study of Child Nutrition and Oral Health in El Salvador. Int J Environ Res Public Health. 2019 Jul 14;16(14):2508. doi: 10.3390/ijerph16142508.
  6. Tsang C, Sokal-Gutierrez K, Patel P, Lewis B, Huang D, Ronsin K, Baral A, Bhatta A, Khadka N, Barkan H, Gurung S. Early Childhood Oral Health and Nutrition in Urban and Rural Nepal. Int J Environ Res Public Health. 2019 Jul 10;16(14):2456. doi: 10.3390/ijerph16142456.
  7. van Meijeren-van Lunteren AW, Voortman T, Elfrink MEC, Wolvius EB, Kragt L. Breastfeeding and Childhood Dental Caries: Results from a Socially Diverse Birth Cohort Study. Caries Res. 2021;55(2):153-161. doi: 10.1159/000514502.
  8. Decker A, Askar H, Tattan M, Taichman R, Wang HL. The assessment of stress, depression, and inflammation as a collective risk factor for periodontal diseases: A systematic review. Clin. Oral Investig. 2020;24:1–12. doi: 10.1007/s00784-019-03089-3.
  9. Almeida ML, Duarte PM, Figueira EA, Lemos JC, Nobre CMG, Miranda TS, de Vasconcelos Gurgel B.C. Effects of a full-mouth disinfection protocol on the treatment of type-2 diabetic and non-diabetic subjects with mild-to-moderate periodontitis: Oneyear clinical outcomes. Clin. Oral Investig. 2020;24:333–341. doi: 10.1007/s00784019-02927-8.
  10. Han SJ, Yi YJ., Bae KH. The association between periodontitis and dyslipidemia according to smoking and harmful alcohol use in a representative sample of Korean adults. Clin. Oral Investig. 2020;24:937–944. doi: 10.1007/s00784-019-02989-8.
  11. Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J. Periodontol. 2018;89(Suppl. S1):S159–S172. doi: 10.1002/JPER.18-0006.
  12. Marra PM, Nucci L, Femiano L, Grassia V, Nastri L, Perillo L. Orthodontic management of a mandibular double-tooth incisor: A case report. Open Dent. J. 2020;14:219–255. doi: 10.2174/1874210602014010219.
  13. Tasdemir I, Erbak Yilmaz H, Narin F, Saglam M. Assessment of saliva and gingival crevicular fluid soluble urokinase plasminogen activator receptor (suPAR), galectin-1, and TNF-alpha levels in periodontal health and disease. J. Periodontal. Res. 2020;55:622–630. doi: 10.1111/jre.12748.
  14. Duarte PM, de Lorenzo Abreu L, Vilela A, Feres M, Giro G, Miranda TS. Protein and mRNA detection of classic cytokines in corresponding samples of serum, gingival tissue and gingival crevicular fluid from subjects with periodontitis. J. Periodontal. Res. 2019;54:174–179. doi: 10.1111/jre.12617.
  15. Nisha KJ, Janam P, Harshakumar K. Identification of a novel salivary biomarker miR-143-3p for periodontal diagnosis: A proof of concept study. J. Periodontol. 2019;90:1149–1159. doi: 10.1002/JPER.18-0729.
  16. Isola G, Polizzi A, Santonocito S, Alibrandi A, Ferlito S. Expression of Salivary and Serum Malondialdehyde and Lipid Profile of Patients with Periodontitis and Coronary Heart Disease. Int. J. Mol. Sci. 2019;20 doi: 10.3390/ijms20236061.
  17. Isola G., Alibrandi A., Rapisarda E., Matarese G., Williams R.C., Leonardi R. Association of vitamin D in patients with periodontitis: A cross-sectional study. J. Periodontal. Res. 2020;55:602–612. doi: 10.1111/jre.12746.
  18. Ghotloo S., Motedayyen H., Amani D., Saffari M., Sattari M. Assessment of microRNA-146a in generalized aggressive periodontitis and its association with disease severity. J. Periodontal. Res. 2019;54:27–32. doi: 10.1111/jre.12538.
  19. Marchetti E., Tecco S., Caterini E., Casalena F., Quinzi V., Mattei A., Marzo G. Alcohol-free essential oils containing mouthrinse efficacy on three-day supragingival plaque regrowth: A randomized crossover clinical trial. Trials. 2017;18:154. doi: 10.1186/s13063-017-1901-z.
  20. Arweiler N.B., Marx V.K., Laugisch O., Sculean A., Auschill T.M. Clinical evaluation of a newly developed chairside test to determine periodontal pathogens. J. Periodontol. 2020;91:387–395. doi: 10.1002/JPER.19-0180.
  21. Bagavad Gita J, George AV, Pavithra N, Chandrasekaran SC, Latchumanadhas K, Gnanamani A. Dysregulation of miR-146a by periodontal pathogens: A risk for acute coronary syndrome. J. Periodontol. 2019;90:756–765. doi: 10.1002/JPER.18-0466.
  22. Isola G, Polizzi A, Iorio-Siciliano V, Alibrandi A, Ramaglia L, Leonardi R. Effectiveness of a nutraceutical agent in the non-surgical periodontal therapy: A randomized, controlled clinical trial. Clin. Oral Investig. 2020 doi: 10.1007/s00784020-03397-z.
  23. Yan K, Lin Q., Tang K, Liu S, Du Y, Yu X, Li S. Substance P participates in periodontitis by upregulating HIF-1alpha and RANKL/OPG ratio. BMC Oral Health. 2020;20:27. doi: 10.1186/s12903-020-1017-9.
  24. Lee JH, Park YS, Kim YT, Kim DH, Jeong SN. Assessment of early discomfort and wound healing outcomes after periodontal surgery with and without enamel matrix derivative: An observational retrospective case-control study. Clin. Oral Investig. 2020;24:229–237. doi: 10.1007/s00784-019-02941-w.
  25. Lo Giudice A, Ortensi L, Farronato M, Lucchese A, Lo Castro E, Isola G. The step further smile virtual planning: Milled versus prototyped mock-ups for the evaluation of the designed smile characteristics. BMC Oral Health. 2020;20:165. doi: 10.1186/s12903-020-01145-z.
  26. Daniele V, Macera L, Taglieri G, Di Giambattista A, Spagnoli G, Massaria A, Messori M, Quagliarini E, Chiappini G, Campanella V, et al. Thermoplastic Disks Used for Commercial Orthodontic Aligners: Complete Physicochemical and Mechanical Characterization. Materials. 2020;13 doi: 10.3390/ma13102386.
  27. Saccomanno S., Quinzi V., Sarhan S., Lagana D., Marzo G. Perspectives of teleorthodontics in the COVID-19 emergency and as a future tool in daily practice. Eur. J. Paediatr. Dent. 2020;21:157–162. doi: 10.23804/ejpd.2020.21.02.12.
  28. Rosa M, Quinzi V, Marzo G. Paediatric Orthodontics Part 1: Anterior open bite in the mixed dentition. Eur. J. Paediatr. Dent. 2019;20:80–82. doi: 10.23804/ejpd.2019.20.01.15.
  29. Lo Giudice A, Quinzi V, Ronsivalle V, Farronato M, Nicotra C, Indelicato F, Isola G. Evaluation of Imaging Software Accuracy for 3-Dimensional Analysis of the Mandibular Condyle. A Comparative Study Using a Surface-to-Surface Matching Technique. Int. J. Environ. Res. Public Health. 2020;17 doi: 10.3390/ijerph17134789.
  30. Lo Giudice A., Leonardi R., Ronsivalle V., Allegrini S., Lagravère M., Marzo G., Isola G. Evaluation of pulp cavity/chamber changes after tooth-borne and bone-borne rapid maxillary expansion. A CBCT study using surface-based superimposition and deviation analysis. Clin. Oral Investig. 2020 doi: 10.1007/s00784-020-03539-3.
  31. Lo Giudice A, Caccianiga G, Crimi S, Cavallini C, Leonardi R. Frequency and type of ponticulus posticus in a longitudinal sample of nonorthodontically treated patients: Relationship with gender, age, skeletal maturity, and skeletal malocclusion. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. 2018;126:291–297. doi: 10.1016/j.oooo.2018.05.001.
  32. Lo Giudice A, Nucera R, Perillo L, Paiusco A, Caccianiga G. Is Low-Level Laser Therapy an Effective Method to Alleviate Pain Induced by Active Orthodontic Alignment Archwire? A Randomized Clinical Trial. J. Evid. Based Dent. Pract. 2019;19:71–78. doi: 10.1016/j.jebdp.2018.11.001.
  33. Lo Giudice A, Rustico L, Caprioglio A, Migliorati M, Nucera R. Evaluation of condylar cortical bone thickness in patient groups with different vertical facial dimensions using cone-beam computed tomography. Odontology. 2020;108:669–675. doi: 10.1007/s10266-020-00510-2.
  34. Lo Giudice A, Spinuzza P, Rustico L, Messina G, Nucera R. Short-term treatment effects produced by rapid maxillary expansion evaluated with computer tomography: A systematic review with meta-analysis. The Korean J. Orthod. 2020;37 doi: 10.1093/ejo/cju100.
  35. Perillo L, Padricelli G, Isola G, Femiano F, Chiodini P, Matarese G. Class II malocclusion division 1: A new classification method by cephalometric analysis. Eur. J. Paediatr. Dent. 2012;13:192–196.
  36. Marra P, Nucci L, Abdolreza J, Perillo L, Itro A, Grassia V. Odontoma in a young and anxious patient associated with unerupted permanent mandibular cuspid: A case report. J. Int. Oral Health. 2020;12:182–186. doi: 10.4103/jioh.jioh_287_19.
  37. Cozzani M., Nucci L., Lupini D., Dolatshahizand H., Fazeli D., Barzkar E., Naeini E., Jamilian A. The ideal insertion angle after immediate loading in Jeil, Storm, and Thunder miniscrews: A 3D-FEM study. Int. Orthod. 2020;18:503–508. doi: 10.1016/j.ortho.2020.03.003.
  38. Cozzani M., Sadri D., Nucci L., Jamilian P., Pirhadirad A.P., Jamilian A. The effect of Alexander, Gianelly, Roth, and MBT bracket systems on anterior retraction: A 3dimensional finite element study. Clin. Oral Investig. 2020;24:1351–1357. doi: 10.1007/s00784-019-03016-6.
  39. Shinjo T., Ishikado A., Hasturk H., Pober D.M., Paniagua S.M., Shah H., Wu I.H., Tinsley L.J., Matsumoto M., Keenan H.A., et al. Characterization of periodontitis in people with type 1 diabetes of 50 years or longer duration. J. Periodontol. 2019;90:565– 575. doi: 10.1002/JPER.18-0735.
  40. Morelli T., Moss K.L., Preisser J.S., Beck J.D., Divaris K., Wu D., Offenbacher S. Periodontal profile classes predict periodontal disease progression and tooth loss. J. Periodontol. 2018;89:148–156. doi: 10.1002/JPER.17-0427.
  41. Bogdan M, Meca AD, Boldeanu MV, Gheorghe DN, Turcu-Stiolica A, Subtirelu MS, Boldeanu L, Blaj M, Botnariu GE, Vlad CE., et al. Possible Involvement of Vitamin C in Periodontal Disease-Diabetes Mellitus Association. Nutrients. 2020;12 doi: 10.3390/nu12020553.
  42. Nastri L, Moretti A, Migliaccio S, Paoletta M, Annunziata M, Liguori S, Toro G, Bianco M, Cecoro G, Guida L, et al. Do Dietary Supplements and Nutraceuticals Have Effects on Dental Implant Osseointegration? A Scoping Review. Nutrients. 2020;12 doi: 10.3390/nu12010268.

How to Cite

Yamaguchi, V. T. M. ., Silva, D. S. da, Oliveira, F. T. D. de, & Kassis, E. N. (2022). Relationship between nutrology and oral health: a systematic review of major clinical findings. International Journal of Nutrology, 15(4). https://doi.org/10.54448/ijn22401