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Published: 06-08-2023

Major approaches to the skin-gut microbiota axis under the light of the nutrology of probiotics and prebiotics: a systematic review

Estação Saúde Brasil Clinic, Araguaína, Centro, Tocantins, Brazil
Healthy skin Gut microbiota Nutrology Probiotics Prebiotics


Introduction: Skin conditions contributed with about 2.0% to the global burden of 306 diseases and injuries in recent years. The microbiota compositions of lesional skin in atopic dermatitis and psoriasis showed distinct differences compared to healthy skin, as well as healthy skin presented a healthy gut microbiota in the light of nutrology. Objective: It was to analyze, through a systematic review, the main considerations on the Skin-Gut microbiota axis, presenting the importance of intestinal health through nutrology, probiotics and prebiotics. Methods: The systematic review rules of the PRISMA Platform were followed. The research was carried out from August to October 2022 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results: A total of 255 articles were found. A total of 76 articles were evaluated in full and 20 articles were included. Current scientific evidence reveals the existence of an important Skin-Gut microbiota axis in the presence of nutrients responsible for this, highlighting the management of dermatoses through probiotics and prebiotics, as well as changes in lifestyle. Conclusion: Management of aesthetically healthy skin includes manipulation of bowel function. Treatments that augment or repair a leaky gut barrier may become important as adjunctive therapy in the management of inflammatory skin conditions and may help to enhance the effectiveness of standard dermal therapy.


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How to Cite

Lima, J. B. de O. (2023). Major approaches to the skin-gut microbiota axis under the light of the nutrology of probiotics and prebiotics: a systematic review. International Journal of Nutrology, 16(2).