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Review
Published: 08-03-2023

Healthy longevity: a systematic review of nutrological and lifestyle aspects

Dr. Rodrigo Junqueira Institute, Rio de Janeiro, Brazil
Dr. Rodrigo Junqueira Institute, Rio de Janeiro, Brazil
Healthy Longevity Nutrology Nutrition Lifestyle

Abstract

Introduction: In the context of healthy longevity, quality of life, genetic, environmental, and lifestyle factors can determine the life expectancy of human beings. Nutrition is a key component affecting our health, and several studies show that nutrition also has the potential to increase lifespan. Objective: It was to carry out a systematic review of the impacts of nutrology and lifestyle on the longevity of human beings, as well as to point out the main dietary and lifestyle care based on the results of clinical studies. Methods: The systematic review rules of the PRISMA Platform were followed. The research was carried out from April to July 2023 in Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 311 articles were found, and 147 articles were evaluated and 47 were included in this systematic review. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 29 studies with a high risk of bias and 51 studies that did not meet GRADE. Most studies showed homogeneity in their results, with X2 =87.3%>50%. There is scientific evidence that nutrients and natural substances of human physiology and biochemistry such as melatonin and coenzyme Q10 control the functions of the immune system. Many metabolic or chronic diseases have been implicated with poor diet and lifestyle. Improved diet quality is associated with reduced all-cause mortality, whereas multivitamins and multimineral supplements can improve life expectancy. Overall well-being is improved when sedentary but sufficiently physically active adults reduce sedentary time and increase physical activity levels. The results of the pandemic indicate there have been a variety of lifestyle changes, physical inactivity, and psychological issues. Still, adults over 40 years old, with children, unemployed, and those living in a macroeconomic region were shown to be more exposed to unhealthy behaviors. The maintenance of dietary intervention through telemedicine can reduce the negative impact of eating habits and physical activity patterns.

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References

  1. Ekmekcioglu C. Nutrition and longevity - From mechanisms to uncertainties. Crit Rev Food Sci Nutr. 2020;60(18):3063-3082. doi: 10.1080/10408398.2019.1676698.
  2. Dominguez LJ, Di Bella G, Veronese N, Barbagallo M. Impact of Mediterranean Diet on Chronic Non-Communicable Diseases and Longevity. Nutrients. 2021 Jun 12;13(6):2028. doi: 10.3390/nu13062028.
  3. Friedman SM. Lifestyle (Medicine) and Healthy Aging. Clin Geriatr Med. 2020 Nov;36(4):645-653. doi: 10.1016/j.cger.2020.06.007.
  4. World Health Organization (WHO). The top 10 causes of death. Disponível em: http://www. who.int/mediacentre/factsheets/fs310/en/. Accessed in: March. 2023.
  5. COVID-19 Map—Johns Hopkins Coronavirus Resource Center. Available online: https://coronavirus.jhu.edu/map.html. Accessed on 18 April 2023.
  6. Decree of the Minister of Health of 20 March 2020 Regarding the Announcement of the State of the Epidemic in the Territory of the Republic of Poland. Available online: http://prawo.sejm.gov.pl/isap.nsf/DocDetails.xsp?id=WDU20200000491 Accessed on 2 April 2023.
  7. Giustino V, Parroco AM, Gennaro A, Musumeci G, Palma A, Battaglia G. Physical Activity Levels and Related Energy Expenditure during COVID-19 Quarantine among the Sicilian Active Population: A Cross-Sectional Online Survey Study. Sustainability 2020, 12, 4356.
  8. Ammar A, Brach M, Trabelsi K, Chtourou H, Boukhris O, Masmoudi L, Bouaziz B, Bentlage E, How D, Ahmed M et al. Effects of COVID-19 Home Confinement on Eating Behaviour and Physical Activity: Results of the ECLB-COVID19 International Online Survey. Nutrients 2020, 12, 1583.
  9. Guthold R, Stevens GA, Riley LM, Bull FC. Worldwide trends in insufficient physical activity from 2001 to 2016: A pooled analysis of 358 population-based surveys with 1·9 million participants. Lancet Glob. Health 2018, 6, e1077–e1086.
  10. Finkelstein EA, Khavjou OA, Thompson H, Trogdon JG, Pan L, Sherry B, Dietz W. Obesity and severe obesity forecasts through 2030. Am. J. Prev. Med. 2012, 42, 563–570.
  11. Ravalli S, Musumeci, G. Coronavirus Outbreak in Italy: Physiological Benefits of Home-Based Exercise During Pandemic. J. Funct. Morphol. Kinesiol. 2020, 5, 31.
  12. Naja F, Hamadeh, R. Nutrition amid the COVID-19 pandemic: A multi-level framework for action. Eur. J. Clin. Nutr. 2020, 1–5.
  13. Zhang Y, Zhang H, Ma X, Di Q. Mental Health Problems during the COVID-19 Pandemics and the Mitigation Effects of Exercise: A Longitudinal Study of College Students in China. Int. J. Environ. Res. Public Health 2020, 17, 3722.
  14. Zabetakis I, Lordan R, Norton C, Tsoupras A. COVID-19: The Inflammation Link and the Role of Nutrition in Potential Mitigation. Nutrients 2020, 12, 1466.
  15. Martinez-Ferran M, de la Guía-Galipienso F, Sanchis-Gomar F, Pareja-Galeano H. Metabolic Impacts of Confinement during the COVID-19 Pandemic Due to Modified Diet and Physical Activity Habits. Nutrients 2020, 12, 1549.
  16. World Health Organization Stay Physically Active during Self-Quarantine. Available online:http://www.euro.who.int/en/health-topics/healthemergencies/coronavirus-covid-19/technical-guidance/stay-physically-activeduring-self-quarantine. Accessed on 20 April 2023.
  17. Chaput JP, Klingenberg L, Astrup A, Sjödin AM. Modern sedentary activities promote overconsumption of food in our current obesogenic environment. Obes. Rev. 2011, 12, e12–e20.
  18. Scully M, Dixon H, Wakefield M. Association between commercial television exposure and fast-food consumption among adults. Public Health Nutr. 2009, 12, 105–110.
  19. World Health Organization Food and Nutrition Tips during Self-Quarantine. Available online: https://www.euro.who.int/en/health-topics/health-emergencies/coronavirus-covid-19/technicalguidance/food-and-nutrition-tipsduring-self-quarantine. Accessed on 15 April 2023.
  20. Calder PC. Nutrition, immunity and COVID-19. BMJ Nutr. Prev. Health 2020.
  21. Valdés-Ramos R, Martnez-Carrillo BE, Aranda-González II, Guadarrama AL, Pardo-Morales RV, Tlatempa P, Jarillo-Luna RA. Diet, exercise and gut mucosal immunity. Proc. Nutr. Soc. 2010, 69, 644–650.
  22. Calder P, Carding S, Christopher G et al. A holistic approach to healthy ageing: how can people live longer, healthier lives? Journal of Human Nutrition and Dietetics. 2018, 31, 4, 439-450.
  23. Scientific Advisory Committee on Nutrition (2018) SACN Statement on Diet, Cognitive Impairment and Dementia. 2018. www.gov.uk/government/publications/sacn-statement-on-diet-cognitive-impairmentand-dementia. Accessed: 22 May 2023.
  24. Dangour A, Andreeva V, Sydenham E et al. Omega 3 fatty acids and cognitive health in older people. British Journal of Nutrition. 2012, 107, Suppl 2, S152S158.
  25. Miller J, Harvey D, Beckett L et al. Vitamin D status and rates of cognitive decline in a multiethnic cohort of older adults. JAMA Neurology. 2015, 72, 11, 12951303.
  26. Davis C, Bryan J, Hodgson J et al. Definition of the Mediterranean diet: a literature review. Nutrients. 2015, 7, 11, 9139-9153.
  27. Willcox D, Scapagnini G, Willcox B. Healthy aging diets other than the Mediterranean: a focus on the Okinawan diet. Mechanisms of Ageing and Development. 2014, 136-137, 148-162.
  28. Yannakoulia M, Kontogianni M, Scarmeas N. Cognitive health and Mediterranean diet: just diet or lifestyle pattern? Ageing Research Reviews. 2015, 20, 74-78.
  29. Zaragoza-Martí A, Cabañero-Martínez M, HurtadoSánchez J et al. Evaluation of Mediterranean diet adherence scores: a systematic review. BMJ Open. 2018, 8, 2, e019033.
  30. Trichopoulou A, Kouris-Blazos A, Wahlqvist M et al. Diet and overall survival in elderly people. BMJ. 1995, 311, 7018, 1457-1460.
  31. Panagiotakos D, Pitsavos C, Stefanadis C. Dietary patterns: a Mediterranean diet score and its relation to clinical and biological markers of cardiovascular disease risk. Nutrition, Metabolism, and Cardiovascular Diseases. 2006, 16, 8, 559-568.
  32. Valls-Pedret C, Sala-Vila A, Serra-Mir M et al. Mediterranean diet and agerelated cognitive decline: a randomized clinical trial. JAMA Internal Medicine. 2015, 175, 7, 1094-1103.
  33. Petersson S, Philippou E. Mediterranean diet, cognitive function, and dementia: a systematic review of the evidence. Advances in Nutrition. 2016, 7, 5, 889-904.
  34. Fernandes BS, Dean OM, Dodd S et al. N-acetylcysteine in depressive symptoms and functionality: a systematic review and meta-analysis. J Clin Psychiatry 2016;77:e457-e66.
  35. Zheng W, Zhang QE, Cai DB et al. N-acetylcysteine for major mental disorders: a systematic review and meta-analysis of randomized controlled trials. Acta Psychiatr Scand 2018;137:391-400.
  36. Breier A, Liffick E, Hummer TA et al. Effects of 12-month, double-blind N-acetyl cysteine on symptoms, cognition and brain morphology in early phase schizophrenia spectrum disorders. Schizophr Res 2018;199:395- 402.
  37. Yolland CO, Phillipou A, Castle DJ et al. Improvement of cognitive function in schizophrenia with N-acetylcysteine: a theoretical review. Nutr Neurosci (in press).
  38. Dean O, Giorlando F, Berk M. N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action. J Psychiatry Neurosci 2011;36:7886.
  39. Reedy J, Krebs-Smith SM, Miller PE et al. Higher diet quality is associated with decreased risk of all-cause, cardiovascular disease, and cancer mortality among older adults. J Nutr 2014;144:881-9.
  40. Wactawski-Wende J, Kotchen JM, Anderson GL et al. Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med 2006; 354:68496.
  41. Jenkins DJ, Spence JD, Giovannucci EL et al. Supplemental vitamins and minerals for CVD prevention and treatment. J Am Coll Cardiol 2018;71: 257084.
  42. Lonn E, Bosch J, Yusuf S et al. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial. JAMA 2005;293:1338-47.
  43. Robertson S, Mountjoy M. A Review of Prevention, Diagnosis, and Treatment of Relative Energy Deficiency in Sport in Artistic (Synchronized) Swimming. Int J Sport Nutr Exerc Metab. 2018;28(4):375-384. doi:10.1123/ijsnem.2017-0329.
  44. Barwais FA, Cuddihy TF, Tomson LM. Physical activity, sedentary behavior and total wellness changes among sedentary adults: a 4-week randomized controlled trial. Health Qual Life Outcomes. 2013;11:183. Published 2013 Oct 29. doi:10.1186/1477-7525-11-183.
  45. Watkins BA. Endocannabinoids, exercise, pain, and a path to health with aging. Mol Aspects Med. 2018;64:68-78. doi:10.1016/j.mam.2018.10.001.
  46. Santesteban Moriones V, Ibáñez Santos J. Ayudas ergogénicas en el deporte [Ergogenic aids in sport]. Nutr Hosp. 2017;34(1):204-215. Published 2017 Feb 1. doi:10.20960/nh.997.
  47. Russell S, Jenkins D, Rynne S, Halson SL, Kelly V. What is mental fatigue in elite sport? Perceptions from athletes and staff. Eur J Sport Sci. 2019;19(10):1367-1376. doi:10.1080/17461391.2019.1618397.

How to Cite

Junqueira, R. A. C., & Pinto, A. C. (2023). Healthy longevity: a systematic review of nutrological and lifestyle aspects. International Journal of Nutrology, 16(3). https://doi.org/10.54448/ijn23302