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Review
Published: 07-14-2025

SIBO: Challenges and Perspectives in Contemporary Gastroenterology

Clinical Hospital of the State University of Campinas. Zeferino Vaz University City - Barão Geraldo, Campinas, Brazil
Dr. Dionisio AM Nunes Clinic- 370 São José Street, Itapiranga, Santa Catarina, Brazil
Medical Clinic. João Wyclif Street, 111, rooms 1701 and 1702, Palhano Gleba, Londrina, Brazil
Medical Clinic, Dom Luís avenue, 1233. Meireles. Salas 1705/1706, Fortaleza, Ceará, Brazil
Bonna Vitta Clinic, May 13th Avenue, 1383, room 302. Fatima. Fortaleza, Ceará, Brazil
Medical Clinic. Pedro de Toledo street, 1800, Vila Clementino, São Paulo, Brazil
Medical Clinic. Paschoal Henrique street, , 600, Jardim Santa Fé, Ourinhos, São Paulo, Brazil
Medical Clinic. Barão Geraldo de Rezende street, 97, room 905, Botafogo, Campinas, São Paulo, Brazil
Medical Clinic. Imperatriz Dona Tereza Cristina avenue, 744, Jardim Guarani, Campinas, São Paulo, Brazil
Medical Clinic. Dr. Renato Paes de Barros street,, 901, room 72, Itaim Bibi, São Paulo, Brazil
Small intestine bacterial overgrowth SIBO Gut microbiome Funcional gastrointestinal diseases SIBO treatment

Abstract

Small Intestinal Bacterial Overgrowth (SIBO) is characterized by an excessive increase in bacteria in an area that normally has a restricted microbiota. This study aims to review the clinical features, diagnostic methods, risk factors, and treatment options for SIBO, with a particular focus on its prevalence in chronic diseases such as irritable bowel syndrome (IBS) and functional diyspepsia, diabetes, and liver diseases. The review highlights the variability in diagnostic methods and the absence of a gold standard, which limits diagnostic accuracy. Among treatment options, antibiotics, probiotics, and herbal therapies (phytotherapy) show potential in symptom management. The need for standardized diagnostic criteria and further research on integrative therapies is emphasized to optimize clinical practice in the treatment of SIBO.

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How to Cite

Reigada, C. P. H., Nunes, D. A. M., Garcia, M. J. M., Cavalcante, H. A., Vidal, D. F. C., Marques, D. P., Gil, L. dos S. G., Garcia, T. M. H. S., Kaffer, E. N., & Haddad, C. M. F. (2025). SIBO: Challenges and Perspectives in Contemporary Gastroenterology. International Journal of Nutrology, 18(S3). https://doi.org/10.54448/ijn25S309